Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1970174 | 0.81 | ATR (0.56) | ATRLMNASMN1; SMN2POLBL3MBTL1 | |
| SCHEMBL6959623 | 0.78 | SMN1; SMN2 (0.45) | ATRLMNASMN1; SMN2POLBL3MBTL1 | |
| SCHEMBL14661066 | 0.77 | NUDT1 (0.52) | LMNAPOLBL3MBTL1CYP1A2KMT2A | |
| SCHEMBL83616 | 0.76 | SMN1; SMN2 (0.59) | LMNASMN1; SMN2L3MBTL1KMT2AMEN1 | |
| SCHEMBL1031057 | 0.76 | SMN1; SMN2 (0.44) | ATRLMNASMN1; SMN2POLBL3MBTL1 | |
| SCHEMBL29486104 | 0.76 | SMN1; SMN2 (0.59) | LMNASMN1; SMN2L3MBTL1KMT2AMEN1 | |
| SCHEMBL6637378 | 0.75 | SMN1; SMN2 (0.42) | ATRLMNASMN1; SMN2POLBL3MBTL1 | |
| SCHEMBL29741249 | 0.75 | KDM4E (0.43) | ATRLMNASMN1; SMN2L3MBTL1KMT2A | |
| SCHEMBL1760077 | 0.75 | KDM4E (0.43) | ATRLMNASMN1; SMN2L3MBTL1KMT2A | |
| SCHEMBL30961407 | 0.75 | SMN1; SMN2 (0.42) | ATRLMNASMN1; SMN2HTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | claimed |
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |