Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | MIF | P14174 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6962141 | 0.89 | TDP1 (0.42) | ACHEIDO1FFAR1ALDH1A1TDP1 | |
| SCHEMBL6971149 | 0.88 | TDP1 (0.44) | ACHEIDO1FFAR1ALDH1A1TDP1 | |
| SCHEMBL6971913 | 0.86 | TDP1 (0.43) | ACHEIDO1ALDH1A1TDP1MAPK1 | |
| SCHEMBL6962298 | 0.85 | FFAR1 (0.41) | ACHEIDO1FFAR1ALDH1A1TDP1 | |
| SCHEMBL15282308 | 0.77 | ALDH1A1 (0.50) | ACHEALDH1A1MAPK1MAPTKMT2A | |
| SCHEMBL26066765 | 0.76 | ALDH1A1 (0.55) | ALDH1A1TDP1MAPK1LMNAKMT2A | |
| SCHEMBL14031523 | 0.76 | ALDH1A1 (0.55) | ALDH1A1TDP1MAPK1LMNAKMT2A | |
| SCHEMBL6968617 | 0.74 | HPGD (0.42) | FFAR1ALDH1A1MAPK1MTNR1AMTNR1B | |
| SCHEMBL6966718 | 0.74 | NPC1 (0.37) | ACHEFFAR1ALDH1A1MTNR1AMTNR1B | |
| SCHEMBL6683261 | 0.73 | HPGD (0.46) | FFAR1ALDH1A1MAPK1CYP1A2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |