Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | MIF | P14174 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6971149 | 0.95 | TDP1 (0.44) | TDP1ACHEALDH1A1LMNAMAPT | |
| SCHEMBL6971913 | 0.93 | TDP1 (0.43) | TDP1ACHEALDH1A1LMNAMAPT | |
| SCHEMBL6967904 | 0.89 | ACHE (0.42) | TDP1ACHEALDH1A1LMNAMAPT | |
| SCHEMBL6962298 | 0.82 | FFAR1 (0.41) | TDP1ACHEALDH1A1MAPTHSD17B10 | |
| SCHEMBL15282308 | 0.74 | ALDH1A1 (0.50) | ACHEALDH1A1MAPTKMT2ATSHR | |
| SCHEMBL296938 | 0.73 | TDP1 (0.78) | TDP1ALDH1A1LMNAKMT2AF2 | |
| SCHEMBL26066765 | 0.73 | ALDH1A1 (0.55) | TDP1ALDH1A1LMNAKMT2ATSHR | |
| SCHEMBL14031523 | 0.73 | ALDH1A1 (0.55) | TDP1ALDH1A1LMNAKMT2ATSHR | |
| SCHEMBL6968617 | 0.71 | HPGD (0.42) | ALDH1A1LMNAMAPTKMT2AHSD17B10 | |
| SCHEMBL6966718 | 0.71 | NPC1 (0.37) | ACHEALDH1A1LMNAMAPTFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |