Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | CDK9 | P50750 | 1/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6683261 | 0.81 | HPGD (0.46) | HPGDMAPTHSD17B10SMN1; SMN2MGLL | |
| SCHEMBL10144329 | 0.77 | TSHR (0.46) | HPGDMAPTHSD17B10SMN1; SMN2MGLL | |
| SCHEMBL12319725 | 0.77 | HPGD (0.42) | HPGDMAPTHSD17B10SMN1; SMN2MGLL | |
| SCHEMBL6832557 | 0.77 | HPGD (0.42) | HPGDMAPTHSD17B10SMN1; SMN2MGLL | |
| SCHEMBL6962298 | 0.77 | FFAR1 (0.41) | HPGDMAPTHSD17B10SMN1; SMN2MGLL | |
| SCHEMBL285027 | 0.77 | NPC1 (0.39) | HPGDMAPTHSD17B10SMN1; SMN2MGLL | |
| SCHEMBL2778717 | 0.76 | TDP1 (0.48) | HPGDMAPTHSD17B10SMN1; SMN2MGLL | |
| Fluoride SCHEMBL27784131 | 0.76 | TSHR (0.45) | HPGDMAPTHSD17B10SMN1; SMN2MGLL | |
| SCHEMBL7078392 | 0.74 | HPGD (0.39) | HPGDMAPTHSD17B10SMN1; SMN2MGLL | |
| SCHEMBL6967904 | 0.74 | ACHE (0.42) | HPGDMAPTHSD17B10SMN1; SMN2MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |