Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.34 |
| ▸ | TUBB | P07437 | 1/20 | 0.34 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6967904 | 0.85 | ACHE (0.42) | FFAR1ACHEHPGDHSD17B10MAPT | |
| SCHEMBL6962141 | 0.82 | TDP1 (0.42) | FFAR1ACHEHSD17B10MAPTSMN1; SMN2 | |
| SCHEMBL6971149 | 0.80 | TDP1 (0.44) | FFAR1ACHEHSD17B10MAPTALDH1A1 | |
| SCHEMBL15282308 | 0.80 | ALDH1A1 (0.50) | ACHEHPGDMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL6971913 | 0.79 | TDP1 (0.43) | ACHEHSD17B10MAPTALDH1A1TSHR | |
| SCHEMBL26066765 | 0.78 | ALDH1A1 (0.55) | SMN1; SMN2ALDH1A1TSHRTDP1NPC1 | |
| SCHEMBL14031523 | 0.78 | ALDH1A1 (0.55) | SMN1; SMN2ALDH1A1TSHRTDP1NPC1 | |
| SCHEMBL6968617 | 0.77 | HPGD (0.42) | FFAR1HPGDHSD17B10MAPTSMN1; SMN2 | |
| SCHEMBL6966718 | 0.77 | NPC1 (0.37) | FFAR1ACHEMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL6683261 | 0.76 | HPGD (0.46) | FFAR1HPGDHSD17B10MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |