Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | YAP1 | P46937 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | BCHE | P06276 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.40 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.40 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.40 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6966742 | 0.91 | YAP1 (0.49) | YAP1KDM4EPKMMAPTMAPK1 | |
| SCHEMBL6964195 | 0.90 | YAP1 (0.45) | YAP1KDM4EPKMMAPTMAPK1 | |
| SCHEMBL6975227 | 0.89 | YAP1 (0.48) | YAP1KDM4EPKMITGB3ITGA2B | |
| SCHEMBL6976104 | 0.89 | YAP1 (0.47) | YAP1KDM4EPKMMAPTMAPK1 | |
| SCHEMBL6971270 | 0.88 | YAP1 (0.46) | YAP1KDM4EPKMITGB3ITGA2B | |
| SCHEMBL6976494 | 0.86 | YAP1 (0.44) | YAP1KDM4EPKMMAPTMAPK1 | |
| SCHEMBL6976461 | 0.85 | HRH4 (0.45) | YAP1KDM4EPKMMAPTMEN1 | |
| SCHEMBL6966451 | 0.82 | KDM4E (0.45) | YAP1KDM4EPKMMAPTBCHE | |
| SCHEMBL6970413 | 0.78 | BCHE (0.47) | YAP1KDM4EPKMITGB3ITGA2B | |
| SCHEMBL6967652 | 0.76 | BCHE (0.51) | YAP1ITGB3ITGA2BMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1098878-B1 | BISPIPERIDINES AS ANTITHROMBOTIC AGENTS | CEPHALON FRANCE (FR) | 2003-12-17 | — | — | EP | disclosed |
| US-6333338-B1 | ANTICOAGULANTS, CARDIOVASCULAR DISORDERS | LABORATOIRE L. LAFON (FR) | 2001-12-25 | — | — | US | disclosed |