Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.43 |
| ▸ | YAP1 | P46937 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | SFN | P31947 | 1/20 | 0.38 |
| ▸ | CCR3 | P51677 | 1/20 | 0.38 |
| ▸ | KLK7 | P49862 | 1/20 | 0.38 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6967985 | 0.85 | YAP1 (0.45) | TP53YAP1LMNAPOLBMAPT | |
| SCHEMBL6975227 | 0.85 | YAP1 (0.48) | YAP1POLBMAPTMEN1KMT2A | |
| SCHEMBL6976104 | 0.85 | YAP1 (0.47) | TP53THRBYAP1LMNAMAPT | |
| SCHEMBL6971270 | 0.84 | YAP1 (0.46) | TP53YAP1LMNAPOLBMAPT | |
| SCHEMBL6966742 | 0.84 | YAP1 (0.49) | TP53YAP1LMNAPOLBMAPT | |
| SCHEMBL6976494 | 0.83 | YAP1 (0.44) | YAP1POLBMAPTMEN1KMT2A | |
| SCHEMBL6964195 | 0.82 | YAP1 (0.45) | TP53YAP1LMNAMAPTMEN1 | |
| SCHEMBL7953780 | 0.76 | KDM4E (0.42) | TP53THRBLMNAPOLBMAPT | |
| SCHEMBL6966451 | 0.76 | KDM4E (0.45) | TP53THRBYAP1LMNAPOLB | |
| SCHEMBL6970413 | 0.75 | BCHE (0.47) | YAP1MAPTKDM4EPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1098878-B1 | BISPIPERIDINES AS ANTITHROMBOTIC AGENTS | CEPHALON FRANCE (FR) | 2003-12-17 | — | — | EP | disclosed |
| US-6333338-B1 | ANTICOAGULANTS, CARDIOVASCULAR DISORDERS | LABORATOIRE L. LAFON (FR) | 2001-12-25 | — | — | US | disclosed |