Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | YAP1 | P46937 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CCKBR | P32239 | 1/20 | 0.39 |
| ▸ | KLK7 | P49862 | 1/20 | 0.38 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.38 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6975227 | 0.90 | YAP1 (0.48) | YAP1KDM4EPKMMEN1KMT2A | |
| SCHEMBL6976104 | 0.89 | YAP1 (0.47) | YAP1KDM4EPKMMEN1KMT2A | |
| SCHEMBL6967985 | 0.88 | YAP1 (0.45) | YAP1KDM4EPKMMEN1KMT2A | |
| SCHEMBL6976494 | 0.87 | YAP1 (0.44) | YAP1KDM4EPKMMEN1KMT2A | |
| SCHEMBL6966742 | 0.85 | YAP1 (0.49) | YAP1KDM4EPKMMEN1KMT2A | |
| SCHEMBL6964195 | 0.85 | YAP1 (0.45) | YAP1KDM4EPKMMEN1KMT2A | |
| SCHEMBL6976461 | 0.84 | HRH4 (0.45) | YAP1KDM4EPKMMEN1KMT2A | |
| SCHEMBL6966451 | 0.80 | KDM4E (0.45) | YAP1KDM4EPKMGPR119MAPT | |
| SCHEMBL6970413 | 0.79 | BCHE (0.47) | YAP1KDM4EPKMGPR119MAPT | |
| SCHEMBL6964406 | 0.76 | KDM4E (0.41) | YAP1KDM4EPKMMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1098878-B1 | BISPIPERIDINES AS ANTITHROMBOTIC AGENTS | CEPHALON FRANCE (FR) | 2003-12-17 | — | — | EP | disclosed |
| US-6333338-B1 | ANTICOAGULANTS, CARDIOVASCULAR DISORDERS | LABORATOIRE L. LAFON (FR) | 2001-12-25 | — | — | US | disclosed |