Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.44 |
| ▸ | YAP1 | P46937 | 3/20 | 0.41 |
| ▸ | BCHE | P06276 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.40 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.40 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.40 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 5/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | STS | P08842 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6964406 | 0.84 | KDM4E (0.41) | KDM4EPKMGPR119YAP1L3MBTL1 | |
| SCHEMBL6969250 | 0.83 | NPC1 (0.43) | KDM4EPKMGPR119YAP1L3MBTL1 | |
| SCHEMBL6967985 | 0.82 | YAP1 (0.45) | KDM4EPKMGPR119YAP1BCHE | |
| SCHEMBL6976104 | 0.82 | YAP1 (0.47) | KDM4EPKMGPR119YAP1L3MBTL1 | |
| SCHEMBL6971137 | 0.82 | KDM4E (0.41) | KDM4EPKMYAP1LMNATP53 | |
| SCHEMBL7943550 | 0.81 | TGFBR1 (0.43) | KDM4EPKMGPR119YAP1LMNA | |
| SCHEMBL6975040 | 0.81 | LMNA (0.42) | KDM4EPKMGPR119LMNATP53 | |
| SCHEMBL6975227 | 0.81 | YAP1 (0.48) | KDM4EPKMGPR119YAP1L3MBTL1 | |
| SCHEMBL7943621 | 0.80 | KDM4E (0.40) | KDM4EPKMGPR119YAP1LMNA | |
| SCHEMBL6975405 | 0.80 | GPR119 (0.45) | KDM4EPKMGPR119YAP1BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1098878-B1 | BISPIPERIDINES AS ANTITHROMBOTIC AGENTS | CEPHALON FRANCE (FR) | 2003-12-17 | — | — | EP | disclosed |
| US-6333338-B1 | ANTICOAGULANTS, CARDIOVASCULAR DISORDERS | LABORATOIRE L. LAFON (FR) | 2001-12-25 | — | — | US | disclosed |