Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | RBP4 | P02753 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6962599 | 0.89 | KMT2A (0.39) | ALDH1A1KMT2ATSHRLMNAMAPT | |
| SCHEMBL6781975 | 0.86 | MAPT (0.41) | ALDH1A1KMT2ATSHRLMNAMAPT | |
| SCHEMBL6963524 | 0.84 | KMT2A (0.43) | ALDH1A1KMT2ATSHRLMNAMAPT | |
| SCHEMBL8702969 | 0.83 | RBP4 (0.49) | ALDH1A1KMT2ALMNAMAPTMAPK1 | |
| SCHEMBL6954279 | 0.83 | KMT2A (0.49) | ALDH1A1KMT2ATSHRLMNAMAPT | |
| SCHEMBL6652808 | 0.83 | RBP4 (0.57) | ALDH1A1KMT2ATSHRLMNAMAPT | |
| SCHEMBL8705827 | 0.83 | LMNA (0.61) | ALDH1A1KMT2ATSHRLMNAMAPT | |
| SCHEMBL8705667 | 0.82 | MAPT (0.49) | ALDH1A1KMT2ALMNAMAPTMAPK1 | |
| SCHEMBL8699252 | 0.82 | MAPT (0.44) | ALDH1A1KMT2ATSHRLMNAMAPT | |
| SCHEMBL8701091 | 0.81 | THRB (0.55) | KMT2ATSHRLMNAMAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0850222-B1 | PIPERAZINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | SAMJIN PHARM CO LTD (KR) | 2003-05-28 | — | — | EP | disclosed |
| US-6028195-A | AN ANTITUMOR AGENT WITH VERY LOW TOXICITIES | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 2000-02-22 | — | — | US | disclosed |