Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | P2RY12 | Q9H244 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | RBP4 | P02753 | 3/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6968075 | 0.89 | ALDH1A1 (0.40) | KMT2AALDH1A1KDM4EHSD17B10TSHR | |
| SCHEMBL8703286 | 0.89 | MAPT (0.46) | KMT2AP2RY12ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL8703804 | 0.86 | KMT2A (0.46) | KMT2AP2RY12ALDH1A1KDM4ERBP4 | |
| SCHEMBL8705088 | 0.85 | HSD17B10 (0.48) | KMT2AP2RY12ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL8704719 | 0.85 | TSHR (0.42) | KMT2AP2RY12ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL8699402 | 0.85 | KMT2A (0.49) | KMT2AP2RY12ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL6956284 | 0.84 | RBP4 (0.43) | KMT2AP2RY12ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL8700061 | 0.84 | MAPT (0.57) | KMT2AALDH1A1KDM4ETSHRRBP4 | |
| SCHEMBL8705064 | 0.84 | HTR1A (0.52) | KMT2AALDH1A1KDM4EHSD17B10TSHR | |
| SCHEMBL8703929 | 0.83 | RBP4 (0.47) | KMT2AALDH1A1KDM4EHSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0850222-B1 | PIPERAZINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | SAMJIN PHARM CO LTD (KR) | 2003-05-28 | — | — | EP | disclosed |
| US-6028195-A | AN ANTITUMOR AGENT WITH VERY LOW TOXICITIES | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 2000-02-22 | — | — | US | disclosed |