Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 15/20 | 0.60 |
| ▸ | MPO | P05164 | 5/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6979505 | 0.91 | HTR1A (0.56) | HTR1AMPOSLC6A4 | |
| SCHEMBL6969718 | 0.80 | HTR1A (0.63) | HTR1AMPOSLC6A4 | |
| SCHEMBL6971407 | 0.80 | HTR1A (0.90) | HTR1AMPOSLC6A4 | |
| SCHEMBL7825328 | 0.79 | HTR1A (0.66) | HTR1AMPOSLC6A4 | |
| SCHEMBL6972781 | 0.77 | HTR1A (0.90) | HTR1AMPOSLC6A4 | |
| SCHEMBL6978453 | 0.76 | HTR1A (0.90) | HTR1AMPOSLC6A4 | |
| SCHEMBL6967208 | 0.75 | HTR1A (0.90) | HTR1AMPOSLC6A4 | |
| SCHEMBL6973561 | 0.75 | HTR1A (0.90) | HTR1AMPOSLC6A4 | |
| SCHEMBL6967864 | 0.74 | HTR1A (0.90) | HTR1AMPOSLC6A4 | |
| SCHEMBL6963008 | 0.74 | HTR1A (0.78) | HTR1AMPOSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140925-B1 | (3,4 DIHYDRO-2H-BENZO[1,4] OXAZINYL-METHYL)- 3-(1H-INDOL-3- YL)-ALKYL -AMINES | WYETH CORP (US) | 2003-04-23 | — | — | EP | disclosed |