Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 17/20 | 0.56 |
| ▸ | MPO | P05164 | 3/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6968536 | 0.91 | HTR1A (0.60) | HTR1AMPOSLC6A4 | |
| SCHEMBL6969718 | 0.91 | HTR1A (0.63) | HTR1AMPOSLC6A4 | |
| SCHEMBL6971407 | 0.77 | HTR1A (0.90) | HTR1AMPOSLC6A4 | |
| SCHEMBL7825328 | 0.76 | HTR1A (0.66) | HTR1AMPOSLC6A4 | |
| SCHEMBL6972781 | 0.74 | HTR1A (0.90) | HTR1AMPOSLC6A4 | |
| SCHEMBL6978453 | 0.74 | HTR1A (0.90) | HTR1AMPOSLC6A4 | |
| SCHEMBL6977474 | 0.72 | MAPT (0.44) | — | |
| SCHEMBL6973561 | 0.72 | HTR1A (0.90) | HTR1AMPOSLC6A4 | |
| SCHEMBL6967864 | 0.72 | HTR1A (0.90) | HTR1AMPOSLC6A4 | |
| SCHEMBL6963008 | 0.71 | HTR1A (0.78) | HTR1AMPOSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140925-B1 | (3,4 DIHYDRO-2H-BENZO[1,4] OXAZINYL-METHYL)- 3-(1H-INDOL-3- YL)-ALKYL -AMINES | WYETH CORP (US) | 2003-04-23 | — | — | EP | disclosed |
| US-6313114-B1 | ANTIDEPRESSANTS | AMERICAN HOME PRODUCTS CORP | 2001-11-06 | — | — | US | disclosed |
| EP-1140925-A1 | (3,4 DIHYDRO-2H-BENZO[1,4] OXAZINYL-METHYL)- 3-(1H-INDOL-3- YL)-ALKYL -AMINES | AMERICAN HOME PRODUCTS CORPORATION (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000040580-A1 | 3,4-DIHYDRO-2H-BENZO[1,4]OXAZINYL-METHYL[3-(1H-INDOL-3-YL)-ALKYL]-AMINES | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-07-13 | — | — | WO | disclosed |