Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 13/20 | 0.90 |
| ▸ | MPO | P05164 | 6/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6977070 | 0.86 | HTR1A (0.89) | HTR1AMPOSLC6A4 | |
| SCHEMBL7825328 | 0.83 | HTR1A (0.66) | HTR1AMPOSLC6A4HTR2A | |
| SCHEMBL6969882 | 0.80 | HTR1A (0.64) | HTR1AMPOSLC6A4HTR2A | |
| SCHEMBL6968536 | 0.80 | HTR1A (0.60) | HTR1AMPOSLC6A4 | |
| SCHEMBL6979505 | 0.77 | HTR1A (0.56) | HTR1AMPOSLC6A4 | |
| SCHEMBL7816824 | 0.76 | HTR1A (0.56) | HTR1ASLC6A4HTR2A | |
| SCHEMBL7817700 | 0.76 | HTR2A (0.56) | HTR1AHTR2A | |
| SCHEMBL7817265 | 0.75 | HTR1A (0.53) | HTR1AHTR2A | |
| SCHEMBL7818119 | 0.75 | HTR1A (0.65) | HTR1AMPOSLC6A4 | |
| SCHEMBL6978453 | 0.74 | HTR1A (0.90) | HTR1AMPOSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140925-B1 | (3,4 DIHYDRO-2H-BENZO[1,4] OXAZINYL-METHYL)- 3-(1H-INDOL-3- YL)-ALKYL -AMINES | WYETH CORP (US) | 2003-04-23 | — | — | EP | claimed |
| EP-1140925-B1 | (3,4 DIHYDRO-2H-BENZO[1,4] OXAZINYL-METHYL)- 3-(1H-INDOL-3- YL)-ALKYL -AMINES | WYETH CORP (US) | 2003-04-23 | — | — | EP | disclosed |
| US-6313114-B1 | ANTIDEPRESSANTS | AMERICAN HOME PRODUCTS CORP | 2001-11-06 | — | — | US | disclosed |