Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6968613 | 1.00 | KDM4E (0.34) | KDM4ESMN1; SMN2TDP1L3MBTL1MAPT | |
| SCHEMBL2812354 | 0.74 | SMN1; SMN2 (0.54) | KDM4ESMN1; SMN2TDP1L3MBTL1MAPT | |
| SCHEMBL2997336 | 0.74 | SMN1; SMN2 (0.54) | KDM4ESMN1; SMN2TDP1L3MBTL1MAPT | |
| SCHEMBL2812357 | 0.74 | SMN1; SMN2 (0.54) | KDM4ESMN1; SMN2TDP1L3MBTL1MAPT | |
| SCHEMBL51251 | 0.73 | TSHR (0.48) | KDM4ETDP1L3MBTL1MAPTTSHR | |
| SCHEMBL6965172 | 0.71 | KDM4E (0.39) | KDM4ESMN1; SMN2TDP1L3MBTL1MAPT | |
| SCHEMBL6965168 | 0.71 | KDM4E (0.39) | KDM4ESMN1; SMN2TDP1L3MBTL1MAPT | |
| SCHEMBL6972237 | 0.71 | HIF1A (0.41) | MAPTTSHR | |
| SCHEMBL6972239 | 0.71 | HIF1A (0.41) | MAPTTSHR | |
| SCHEMBL1426474 | 0.70 | NPC1 (0.43) | SMN1; SMN2L3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220055996-A1 | METHOD OF PREPARING MALONONITRILE OXIME ETHER COMPOUND AND INTERMEDIATE COMPOUND | SHENYANG SINOCHEM AGROCHEMICALS R & D CO LTD (CN) | 2022-02-24 | — | — | US | claimed |
| EP-3822253-A1 | METHOD FOR PREPARING PROPANEDINITRILE OXIME ETHER COMPOUND AND INTERMEDIATE COMPOUND | Shenyang Sinochem Agrochemicals R&D Co., Ltd. (CN) | 2021-05-19 | — | — | EP | claimed |
| US-11952355-B2 | Method of preparing malononitrile oxime ether compound and intermediate compound | SHENYANG SINOCHEM AGROCHEMICALS R&D CO., LTD. (CN) | 2024-04-09 | — | — | US | disclosed |
| US-20220055996-A1 | METHOD OF PREPARING MALONONITRILE OXIME ETHER COMPOUND AND INTERMEDIATE COMPOUND | SHENYANG SINOCHEM AGROCHEMICALS R & D CO LTD (CN) | 2022-02-24 | — | — | US | disclosed |
| CN-110713443-B | Process for preparing malononitrile oxime ether compounds and intermediate compounds | 沈阳中化农药化工研发有限公司 | 2022-01-28 | — | — | CN | disclosed |
| EP-3822253-A1 | METHOD FOR PREPARING PROPANEDINITRILE OXIME ETHER COMPOUND AND INTERMEDIATE COMPOUND | Shenyang Sinochem Agrochemicals R&D Co., Ltd. (CN) | 2021-05-19 | — | — | EP | disclosed |
| CN-110713443-A | Process for preparing malononitrile oxime ether compounds and intermediate compounds | 沈阳中化农药化工研发有限公司 | 2020-01-21 | — | — | CN | disclosed |
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11952355-B2 | Method of preparing malononitrile oxime ether compound and intermediate compound | CYP2E1, CYP3A4, POR | KDM4E 524/4885SMN1; SMN2 3300/4885TDP1 4678/4885 |
| US-20220055996-A1 | METHOD OF PREPARING MALONONITRILE OXIME ETHER COMPOUND AND INTERMEDIATE COMPOUND | CYP2B6, CYP2D6, CYP2A6 | KDM4E 893/4885SMN1; SMN2 4024/4885TDP1 4675/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.