Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6973826 | 0.90 | ALDH1A1 (0.34) | ALDH1A1LMNAMAPTGAA | |
| SCHEMBL6974402 | 0.87 | TDP1 (0.32) | — | |
| SCHEMBL6967136 | 0.87 | GAA (0.33) | GAA | |
| SCHEMBL6959790 | 0.85 | ALDH1A1 (0.31) | ALDH1A1LMNAMAPT | |
| SCHEMBL6973102 | 0.85 | ALOX5 (0.36) | MAPT | |
| SCHEMBL7084653 | 0.84 | SETDB1 (0.33) | — | |
| SCHEMBL6967170 | 0.83 | SMN1; SMN2 (0.35) | ALDH1A1LMNAMAPTGAA | |
| SCHEMBL7080069 | 0.83 | S1PR3 (0.37) | ALDH1A1 | |
| SCHEMBL6961868 | 0.83 | F2 (0.31) | ALDH1A1LMNAMAPTGAA | |
| SCHEMBL7085972 | 0.82 | GRIN1 (0.37) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786455-B1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO (JP) | 2003-12-03 | — | — | EP | disclosed |
| US-6147097-A | METHOD FOR TREATING AIDS | SHIONOGI & CO., LTD. (JP) | 2000-11-14 | — | — | US | disclosed |
| US-5910506-A | IMIDAZOLE DERIVATIVES, E.G.5-(3,5-DICHLOROPHENYLTHIO)-1,2-DIMETHYL-4-ISOPROPYL-1H-IMIDAZOLE; VIRICIDES; AIDS; NONTOXIC | SHIONOGI & CO., LTD. (JP) | 1999-06-08 | — | — | US | disclosed |
| EP-0786455-A1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 1997-07-30 | — | — | EP | disclosed |