Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 5/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.36 |
| ▸ | SMO | Q99835 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6975773 | 0.80 | RAB9A (0.38) | RAB9AALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL6969091 | 0.75 | MAPK14 (0.42) | CHRM3KDRMAPK14SMOALDH1A1 | |
| SCHEMBL6486377 | 0.75 | MAPK14 (0.63) | MAPK14SMORAB9ATSHRMEN1 | |
| SCHEMBL7805580 | 0.73 | MAPK14 (0.56) | MAPK14SMORAB9ATSHRMEN1 | |
| SCHEMBL6972610 | 0.73 | PDE4D (0.41) | ALDH1A1MEN1KMT2A | |
| SCHEMBL6969088 | 0.72 | MAPK14 (0.61) | MAPK14SMO | |
| SCHEMBL6978401 | 0.70 | MAPK14 (0.52) | MAPK14SMO | |
| SCHEMBL7109855 | 0.68 | MAPK14 (0.59) | MAPK14SMORAB9AMEN1KMT2A | |
| SCHEMBL6571676 | 0.64 | MAPK14 (0.47) | MAPK14SMO | |
| SCHEMBL6487036 | 0.63 | MAPK14 (0.66) | KDRMAPK14SMORAB9ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1115707-B1 | BENZAMIDE DERIVATIVES AND THER USE AS CYTOKINE INHIBITORS | ASTRAZENECA AB (SE) | 2003-11-12 | — | — | EP | claimed |
| EP-1115707-B1 | BENZAMIDE DERIVATIVES AND THER USE AS CYTOKINE INHIBITORS | ASTRAZENECA AB (SE) | 2003-11-12 | — | — | EP | disclosed |