Sugi Predict

Sugi Predict / Compounds / SCHEMBL696918

SCHEMBL696918

SCHEMBL696918

CCC(C)COC(=O)OC

nearest known ligand 0.47

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 1/20 0.47
▸ CA1 P00915 1/20 0.38
▸ CA2 P00918 1/20 0.38
▸ ALDH1A1 P00352 1/20 0.36
▸ SMN1; SMN2 Q16637 3/20 0.34
▸ MMP1 P03956 1/20 0.34
▸ MMP2 P08253 1/20 0.34
▸ MMP3 P08254 1/20 0.34
▸ MGAM O43451 1/20 0.33
▸ GAA P10253 1/20 0.33
▸ SI P14410 1/20 0.33
▸ MGAM2 Q2M2H8 1/20 0.33
▸ FFAR1 O14842 1/20 0.33
▸ SOAT1 P35610 1/20 0.33
▸ CA14 Q9ULX7 1/20 0.32
▸ ZDHHC7 Q9NXF8 1/20 0.31
▸ TSHR P16473 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1127763 0.90 MAPT (0.50) MAPTCA1CA2ALDH1A1SMN1; SMN2
SCHEMBL25392616 0.90 MAPT (0.50) MAPTCA1CA2ALDH1A1SMN1; SMN2
Bicarbonate SCHEMBL28397287 0.86 MAPT (0.52) MAPTALDH1A1SMN1; SMN2FFAR1SOAT1
SCHEMBL14244980 0.86 SOAT1 (0.50) MAPTALDH1A1SMN1; SMN2FFAR1SOAT1
SCHEMBL18924829 0.84 MAPT (0.46) MAPTCA2ALDH1A1SMN1; SMN2FFAR1
SCHEMBL5724509 0.84 ALDH1A1 (0.59) MAPTALDH1A1MGAMGAASI
SCHEMBL17173532 0.82 MAPT (0.44) MAPTALDH1A1FFAR1SOAT1TSHR
SCHEMBL696917 0.82 MAPT (0.44) MAPTALDH1A1FFAR1SOAT1TSHR
SCHEMBL27871158 0.82 MAPT (0.44) MAPTALDH1A1FFAR1SOAT1
SCHEMBL5859548 0.81 MGAM (0.50) MAPTCA1CA2ALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170226269-A1 POLYMER COMPRISING REPEATING UNITS CONSISTING OF A SUBSTITUTED PYRROLE RING AND PRODUCTS OBTAINED BY COMBINING SAID POLYMERS WITH CARBON ALLOTROPES POLITECNICO DI MILANO (IT) 2017-08-10 — — US disclosed
US-20170226269-A1 POLYMER COMPRISING REPEATING UNITS CONSISTING OF A SUBSTITUTED PYRROLE RING AND PRODUCTS OBTAINED BY COMBINING SAID POLYMERS WITH CARBON ALLOTROPES POLITECNICO DI MILANO (IT) 2017-08-10 — — US disclosed
EP-2423199-A1 Substituted imidazoles and their use as pesticides Pfizer Limited (GB) 2012-02-29 — — EP disclosed
EP-2320732-A2 SUBSTITUTED IMIDAZOLE COMBINATIONS Pfizer Inc. (US) 2011-05-18 — — EP disclosed
EP-1981853-B1 SUBSTITUTED IMIDAZOLES AND THEIR USE AS PESTICIDES PFIZER LTD (GB) 2011-04-13 — — EP disclosed
US-7825149-B2 Substituted imidazoles PFIZER LIMITED (GB) 2010-11-02 — — US disclosed
WO-2010020896-A2 SUBSTITUTED IMIDAZOLE COMBINATIONS PFIZER INC. (US) 2010-02-25 — — WO disclosed
US-20090312326-A1 SUBSTITUTED IMIDAZOLES PFIZER LIMITED (GB) 2009-12-17 — — US disclosed
US-7592362-B2 Substituted imidazoles PFIZER LIMITED (GB) 2009-09-22 — — US disclosed
US-7547718-B2 Substituted imidazoles PFIZER LIMITED (GB) 2009-06-16 — — US disclosed
US-20080161394-A1 Cosmetic composition comprising at least one volatile carbonic acid ester L'OREAL S.A. (FR) 2008-07-03 — — US disclosed
US-20080125473-A1 SUBSTITUTED IMIDAZOLES PFIZER LIMITED (GB) 2008-05-29 — — US disclosed
US-20080119536-A1 SUBSTITUTED IMIDAZOLES PFIZER LIMITED (GB) 2008-05-22 — — US disclosed
WO-2007083207-A1 SUBSTITUTED IMIDAZOLES AND THEIR USE AS PESTICIDES PFIZER LIMITED (GB) 2007-07-26 — — WO disclosed
US-20070167506-A1 SUBSTITUTED IMIDAZOLES PFIZER INC. (US) 2007-07-19 — — US disclosed
US-7198827-B1 Nematic liquid crystal composition and liquid crystal display device using the same DAINIPPON INK AND CHEMICALS, INC. (JP) 2007-04-03 — — US disclosed
EP-1340757-B1 1-METHYLCARBAPENEM DERIVATIVES SANKYO CO (JP) 2006-10-11 — — EP disclosed
US-7001897-B2 1-methylcarbapenem derivatives SANKYO COMPANY, LIMITED (JP) 2006-02-21 — — US disclosed
US-20040014962-A1 1-Methylcarbapenem derivatives SANKYO COMPANY, LIMITED (JP) 2004-01-22 — — US disclosed
EP-1340757-A1 1-METHYLCARBAPENEM DERIVATIVES Sankyo Company, Limited (JP) 2003-09-03 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080125473-A1 SUBSTITUTED IMIDAZOLES ABL1, TYR, CYP3A4 MAPT 316/4885CA1 3378/4885CA2 826/4885
US-20040014962-A1 1-Methylcarbapenem derivatives CD14, CPT1A, ACMSD MAPT 2574/4885CA1 2558/4885CA2 2546/4885
US-20090312326-A1 SUBSTITUTED IMIDAZOLES ABL1, TYR, CYP3A4 MAPT 316/4885CA1 3378/4885CA2 826/4885
US-20070167506-A1 SUBSTITUTED IMIDAZOLES ABL1, TYR, CYP3A4 MAPT 316/4885CA1 3378/4885CA2 826/4885
US-20080119536-A1 SUBSTITUTED IMIDAZOLES ABL1, TYR, CYP3A4 MAPT 316/4885CA1 3378/4885CA2 826/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.