Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR6 | P46095 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | DRD4 | P21917 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | PRKAA2 | P54646 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 2/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | TNF | P01375 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6966543 | 0.99 | GPR6 (0.36) | GPR6DRD2DRD4LMNAMAPT | |
| Hydrochloric Acid SCHEMBL6961096 | 0.91 | KDM4E (0.34) | LMNASMN1; SMN2KDM4EALDH1A1NPSR1 | |
| Hydrochloric Acid SCHEMBL6967875 | 0.89 | KDM4E (0.38) | LMNAMAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL6957770 | 0.88 | THRB (0.35) | DHFR | |
| SCHEMBL6967410 | 0.87 | KCNH3 (0.34) | LMNAMAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL6954449 | 0.86 | NOTUM (0.36) | LMNAMAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL6967711 | 0.86 | TRPC3 (0.37) | LMNAMEN1KMT2AKDM4ENPSR1 | |
| SCHEMBL6963858 | 0.86 | PIK3CD (0.36) | DHFR | |
| SCHEMBL6967978 | 0.86 | PIK3CD (0.36) | DHFR | |
| SCHEMBL6963603 | 0.85 | KCNH3 (0.36) | LMNAMAPTSMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1015444-B1 | PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP LTD (KR) | 2003-05-28 | — | — | EP | claimed |