Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 10/20 | 0.46 |
| ▸ | HTR1A | P08908 | 7/20 | 0.46 |
| ▸ | DRD3 | P35462 | 6/20 | 0.46 |
| ▸ | DRD2 | P14416 | 10/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 5/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 3/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6971866 | 0.85 | DRD2 (0.46) | HTR2AHTR1ADRD3DRD2MCHR1 | |
| SCHEMBL6965352 | 0.85 | DRD3 (0.58) | HTR2AHTR1ADRD3DRD2DRD4 | |
| Hydrochloric Acid SCHEMBL6973062 | 0.84 | DRD2 (0.46) | HTR2AHTR1ADRD3DRD2MCHR1 | |
| SCHEMBL6964674 | 0.78 | DRD2 (0.48) | HTR2AHTR1ADRD3DRD2MCHR1 | |
| SCHEMBL7465752 | 0.73 | CHRM1 (0.51) | HTR2ADRD2MCHR1HRH1CHRM1 | |
| SCHEMBL7468275 | 0.73 | DRD2 (0.63) | HTR2AHTR1ADRD3DRD2MCHR1 | |
| SCHEMBL6969702 | 0.73 | DRD2 (0.46) | HTR2AHTR1ADRD3DRD2MCHR1 | |
| SCHEMBL6971120 | 0.72 | DRD2 (0.42) | HTR2AHTR1ADRD3DRD2MCHR1 | |
| Hydrochloric Acid SCHEMBL6969809 | 0.72 | DRD2 (0.46) | HTR2ADRD3DRD2MCHR1DRD4 | |
| SCHEMBL7464940 | 0.71 | CHRM1 (0.55) | HTR2ADRD3DRD2MCHR1HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934312-B1 | 1,4-DISUBSTITUTED PIPERAZINES | NOVO NORDISK AS (DK) | 2003-03-19 | — | — | EP | claimed |