Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 11/20 | 0.48 |
| ▸ | HTR2A | P28223 | 5/20 | 0.48 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.48 |
| ▸ | HTR1A | P08908 | 2/20 | 0.45 |
| ▸ | HTR7 | P34969 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 4/20 | 0.43 |
| ▸ | DRD4 | P21917 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6971120 | 0.93 | DRD2 (0.42) | DRD2HTR2AMCHR1HTR1AHTR7 | |
| SCHEMBL6965928 | 0.85 | DRD2 (0.59) | DRD2DRD3DRD4CHRM1 | |
| SCHEMBL6969702 | 0.85 | DRD2 (0.46) | DRD2HTR2AMCHR1HTR1AHTR7 | |
| Hydrochloric Acid SCHEMBL6972143 | 0.85 | DRD2 (0.58) | DRD2DRD3DRD4CHRM1 | |
| Hydrochloric Acid SCHEMBL6969809 | 0.85 | DRD2 (0.46) | DRD2HTR2AMCHR1DRD3DRD4 | |
| SCHEMBL6957294 | 0.81 | OPRK1 (0.44) | DRD2HTR2AMCHR1HTR1AHTR7 | |
| SCHEMBL6964899 | 0.80 | HRH1 (0.40) | DRD2HTR1AHTR7 | |
| SCHEMBL6971825 | 0.79 | DRD2 (0.51) | DRD2DRD3DRD4CHRM1 | |
| SCHEMBL6965947 | 0.79 | HRH1 (0.43) | DRD2HTR2AMCHR1HTR1AHTR7 | |
| SCHEMBL6955492 | 0.79 | DRD2 (0.54) | DRD2HTR2AHTR1ADRD3DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934312-B1 | 1,4-DISUBSTITUTED PIPERAZINES | NOVO NORDISK AS (DK) | 2003-03-19 | — | — | EP | claimed |