Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 7/20 | 0.42 |
| ▸ | HTR2A | P28223 | 4/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.41 |
| ▸ | DRD3 | P35462 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GMNN | O75496 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6964674 | 0.93 | DRD2 (0.48) | DRD2HTR2AMCHR1DRD3MEN1 | |
| SCHEMBL6965947 | 0.88 | HRH1 (0.43) | DRD2HTR2AMCHR1ADRA1ADRD3 | |
| Hydrochloric Acid SCHEMBL6971834 | 0.87 | HRH1 (0.42) | DRD2HTR2AMCHR1ADRA1ADRD3 | |
| SCHEMBL6966481 | 0.85 | KDM4E (0.42) | DRD2HTR2AMCHR1DRD3MEN1 | |
| SCHEMBL6955492 | 0.84 | DRD2 (0.54) | DRD2HTR2AADRA1DADRA1ADRD3 | |
| SCHEMBL6969702 | 0.79 | DRD2 (0.46) | DRD2HTR2AMCHR1DRD3KMT2A | |
| SCHEMBL6965928 | 0.79 | DRD2 (0.59) | DRD2ADRA1DADRA1AADRA1BDRD3 | |
| SCHEMBL6970693 | 0.79 | CCR1 (0.41) | DRD2HTR2AADRA1DADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL6972143 | 0.78 | DRD2 (0.58) | DRD2ADRA1DADRA1AADRA1BDRD3 | |
| Hydrochloric Acid SCHEMBL6969809 | 0.78 | DRD2 (0.46) | DRD2HTR2AMCHR1DRD3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934312-B1 | 1,4-DISUBSTITUTED PIPERAZINES | NOVO NORDISK AS (DK) | 2003-03-19 | — | — | EP | claimed |