Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | CASP1 | P29466 | 2/20 | 0.37 |
| ▸ | CASP7 | P55210 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 3/20 | 0.36 |
| ▸ | RXRA | P19793 | 4/20 | 0.35 |
| ▸ | RXRB | P28702 | 4/20 | 0.35 |
| ▸ | RXRG | P48443 | 4/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | IGF1R | P08069 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6970151 | 0.76 | PARP1 (0.39) | KDM4EALDH1A1GAAHSD17B10CASP1 | |
| SCHEMBL11981462 | 0.74 | KDM4E (0.44) | KDM4EALDH1A1GAAHSD17B10CASP1 | |
| SCHEMBL3500989 | 0.73 | PARP1 (0.44) | KDM4EALDH1A1GAAHSD17B10CASP1 | |
| SCHEMBL9176149 | 0.71 | SRC (0.62) | KDM4EPARP1RXRARXRBRXRG | |
| SCHEMBL19178086 | 0.70 | RXRA (0.33) | KDM4EALDH1A1GAAGLAHPGD | |
| SCHEMBL29187807 | 0.69 | PARP1 (0.47) | PARP1IGF1R | |
| SCHEMBL6975538 | 0.69 | RXRA (0.37) | KDM4EALDH1A1GAAPARP1RXRA | |
| SCHEMBL10914542 | 0.68 | KDM4E (0.51) | KDM4EALDH1A1GAAHSD17B10CASP1 | |
| SCHEMBL13348032 | 0.68 | ALDH1A1 (0.43) | KDM4EALDH1A1GAAHSD17B10CASP1 | |
| SCHEMBL31275828 | 0.66 | IGF1R (0.43) | HPGDPARP1IGF1RMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0931070-B1 | HETAROYL CYCLOHEXANEDIONE DERIVATIVES WITH HERBICIDAL EFFECT | BASF AG (DE) | 2003-03-19 | — | — | EP | disclosed |