Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | GRM5 | P41594 | 3/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.38 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6972112 | 0.82 | LMNA (0.39) | ALDH1A1HPGDMAPTKDM4ELMNA | |
| SCHEMBL6973574 | 0.82 | KMT2A (0.41) | ALDH1A1HPGDMAPTKDM4ELMNA | |
| SCHEMBL7084513 | 0.82 | LMNA (0.39) | ALDH1A1HPGDMAPTKDM4ELMNA | |
| SCHEMBL6973394 | 0.78 | MEN1 (0.42) | ALDH1A1HPGDMAPTKDM4ELMNA | |
| SCHEMBL6973812 | 0.76 | LMNA (0.39) | ALDH1A1HPGDMAPTKDM4ELMNA | |
| SCHEMBL6964412 | 0.76 | ALOX12 (0.41) | ALDH1A1HPGDMAPTKDM4ELMNA | |
| SCHEMBL6964721 | 0.76 | ALDH1A1 (0.35) | ALDH1A1HPGDMAPTKDM4ELMNA | |
| SCHEMBL6969756 | 0.75 | ALOX12 (0.40) | ALDH1A1HPGDMAPTKDM4ELMNA | |
| SCHEMBL7087095 | 0.73 | LMNA (0.38) | ALDH1A1HPGDMAPTKDM4ELMNA | |
| SCHEMBL6961944 | 0.73 | ALDH1A1 (0.40) | ALDH1A1HPGDMAPTKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786455-B1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO (JP) | 2003-12-03 | — | — | EP | disclosed |