Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6971802 | 0.91 | SMN1; SMN2 (0.44) | LMNASMN1; SMN2KMT2AMEN1ALDH1A1 | |
| SCHEMBL6969348 | 0.89 | SMN1; SMN2 (0.45) | LMNAHTTUSP2SMN1; SMN2KMT2A | |
| SCHEMBL6962161 | 0.89 | LMNA (0.49) | LMNAHTTUSP2SMN1; SMN2KMT2A | |
| SCHEMBL6964153 | 0.89 | SMN1; SMN2 (0.46) | LMNAHTTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL6955643 | 0.88 | L3MBTL1 (0.46) | SMN1; SMN2KMT2AMEN1ALDH1A1POLB | |
| SCHEMBL6966483 | 0.87 | SMN1; SMN2 (0.44) | LMNASMN1; SMN2KMT2AMEN1ALDH1A1 | |
| SCHEMBL6969382 | 0.87 | LMNA (0.55) | LMNAHTTUSP2KMT2AMEN1 | |
| SCHEMBL6965972 | 0.87 | SMN1; SMN2 (0.42) | LMNASMN1; SMN2KMT2AMEN1MGLL | |
| SCHEMBL6955924 | 0.87 | LMNA (0.47) | LMNAHTTUSP2KMT2AMEN1 | |
| SCHEMBL6960505 | 0.85 | LMNA (0.52) | LMNAHTTUSP2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0620216-B1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO (JP) | 2003-01-08 | — | — | EP | disclosed |
| EP-0620216-A1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-19 | — | — | EP | disclosed |