Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6971802 | 0.96 | SMN1; SMN2 (0.44) | SMN1; SMN2KMT2AMEN1ALDH1A1POLB | |
| SCHEMBL6969348 | 0.91 | SMN1; SMN2 (0.45) | SMN1; SMN2KMT2AMEN1ALDH1A1POLB | |
| SCHEMBL6955643 | 0.90 | L3MBTL1 (0.46) | SMN1; SMN2KMT2AMEN1ALDH1A1POLB | |
| SCHEMBL6970194 | 0.87 | LMNA (0.52) | SMN1; SMN2KMT2AMEN1ALDH1A1POLB | |
| SCHEMBL6969459 | 0.87 | ALDH1A1 (0.46) | SMN1; SMN2KMT2AMEN1ALDH1A1RAB9A | |
| SCHEMBL6964153 | 0.86 | SMN1; SMN2 (0.46) | SMN1; SMN2KMT2AMEN1ALDH1A1POLB | |
| SCHEMBL6965972 | 0.85 | SMN1; SMN2 (0.42) | SMN1; SMN2KMT2AMEN1ALDH1A1POLB | |
| SCHEMBL6964263 | 0.85 | ALDH1A1 (0.42) | SMN1; SMN2KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL6970661 | 0.83 | ALDH1A1 (0.46) | SMN1; SMN2KMT2AMEN1ALDH1A1RAB9A | |
| SCHEMBL6969398 | 0.83 | ALDH1A1 (0.42) | KMT2AMEN1ALDH1A1POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0620216-B1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO (JP) | 2003-01-08 | — | — | EP | disclosed |
| US-5521170-A | VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-28 | — | — | US | disclosed |
| EP-0620216-A1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-19 | — | — | EP | disclosed |