Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6970661 | 0.90 | ALDH1A1 (0.46) | LMNAHTTUSP2MAPTAVPR2 | |
| SCHEMBL6960505 | 0.90 | LMNA (0.52) | LMNAHTTUSP2TSHRMAPT | |
| SCHEMBL6969797 | 0.88 | LMNA (0.44) | LMNAHTTUSP2MAPTAVPR2 | |
| SCHEMBL6962852 | 0.88 | CA1 (0.43) | LMNAHTTUSP2TSHRMAPT | |
| SCHEMBL6959155 | 0.87 | LMNA (0.50) | LMNAHTTUSP2TSHRMAPT | |
| SCHEMBL6970194 | 0.87 | LMNA (0.52) | LMNAHTTUSP2TSHRMAPT | |
| SCHEMBL6960127 | 0.87 | NPSR1 (0.49) | LMNAHTTUSP2TSHRMAPT | |
| SCHEMBL6969459 | 0.86 | ALDH1A1 (0.46) | LMNAHTTUSP2MAPTAVPR2 | |
| SCHEMBL6967645 | 0.86 | LOXL2 (0.40) | LMNAHTTUSP2NPSR1PPARG | |
| SCHEMBL6962161 | 0.83 | LMNA (0.49) | LMNAHTTUSP2TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0620216-B1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO (JP) | 2003-01-08 | — | — | EP | disclosed |
| US-5521170-A | VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-28 | — | — | US | disclosed |
| EP-0620216-A1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-19 | — | — | EP | disclosed |