Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.34 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL696078 | 1.00 | L3MBTL1 (0.39) | L3MBTL1LMNAMAPK1HTTMAPT | |
| SCHEMBL696077 | 1.00 | L3MBTL1 (0.39) | L3MBTL1LMNAMAPK1HTTMAPT | |
| SCHEMBL695964 | 0.81 | LMNA (0.47) | L3MBTL1LMNAMAPK1HTTMAPT | |
| SCHEMBL695965 | 0.81 | LMNA (0.47) | L3MBTL1LMNAMAPK1HTTMAPT | |
| SCHEMBL695779 | 0.81 | L3MBTL1 (0.36) | L3MBTL1LMNAMAPK1HTTNPC1 | |
| SCHEMBL695780 | 0.81 | L3MBTL1 (0.36) | L3MBTL1LMNAMAPK1HTTNPC1 | |
| SCHEMBL6345644 | 0.81 | L3MBTL1 (0.36) | L3MBTL1LMNAMAPK1HTTNPC1 | |
| SCHEMBL6345600 | 0.81 | LMNA (0.47) | L3MBTL1LMNAMAPK1HTTMAPT | |
| SCHEMBL6972037 | 0.80 | NPC1 (0.36) | LMNAHTTMAPTPKMCDK5 | |
| SCHEMBL6972040 | 0.80 | NPC1 (0.36) | LMNAHTTMAPTPKMCDK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |