Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.34 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL696078 | 1.00 | L3MBTL1 (0.39) | L3MBTL1LMNAMAPK1HTTMAPT | |
| SCHEMBL6970352 | 1.00 | L3MBTL1 (0.39) | L3MBTL1LMNAMAPK1HTTMAPT | |
| SCHEMBL695964 | 0.81 | LMNA (0.47) | L3MBTL1LMNAMAPK1HTTMAPT | |
| SCHEMBL695965 | 0.81 | LMNA (0.47) | L3MBTL1LMNAMAPK1HTTMAPT | |
| SCHEMBL695779 | 0.81 | L3MBTL1 (0.36) | L3MBTL1LMNAMAPK1HTTNPC1 | |
| SCHEMBL695780 | 0.81 | L3MBTL1 (0.36) | L3MBTL1LMNAMAPK1HTTNPC1 | |
| SCHEMBL6345644 | 0.81 | L3MBTL1 (0.36) | L3MBTL1LMNAMAPK1HTTNPC1 | |
| SCHEMBL6345600 | 0.81 | LMNA (0.47) | L3MBTL1LMNAMAPK1HTTMAPT | |
| SCHEMBL6972037 | 0.80 | NPC1 (0.36) | LMNAHTTMAPTPKMCDK5 | |
| SCHEMBL6972040 | 0.80 | NPC1 (0.36) | LMNAHTTMAPTPKMCDK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9770027-B2 | Heteroarylpiperidine and -piperazine derivatives as fungicides | BAYER CROPSCIENCE AG (DE) | 2017-09-26 | — | — | US | disclosed |
| US-20150351403-A1 | Heteroarylpiperidine and -piperazine derivatives as fungicides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2015-12-10 | — | — | US | disclosed |
| US-9150565-B2 | Heteroarylpiperidine and -piperazine derivatives as fungicides | BAYER CROPSCIENCE AG (DE) | 2015-10-06 | — | — | US | disclosed |
| US-20140206646-A1 | Heteroarylpiperidine and -piperazine derivatives as fungicides | BAYER CROPSCIENCE AG (DE) | 2014-07-24 | — | — | US | disclosed |
| US-8759527-B2 | Heteroarylpiperidine and -piperazine derivatives as fungicides | BAYER CROPSCIENCE AG (DE) | 2014-06-24 | — | — | US | disclosed |
| EP-2423210-A1 | Heteroarylpiperidine and heteroarylpiperazine derivatives as fungicides | Bayer CropScience AG (DE) | 2012-02-29 | — | — | EP | disclosed |
| US-20050101783-A1 | N-(heterocycle-methyl)alkylamine derivative, process for producing the same, and bactericide | KUREHA CORPORATION (JP) | 2005-05-12 | — | — | US | disclosed |
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050101783-A1 | N-(heterocycle-methyl)alkylamine derivative, process for producing the same, and bactericide | HBZ, ACMSD, HDHD5 | L3MBTL1 1563/4885LMNA 2729/4885MAPK1 1370/4885 |
| US-20150351403-A1 | Heteroarylpiperidine and -piperazine derivatives as fungicides | CYP1A1, PRXL2A, CYP1A2 | L3MBTL1 1885/4885LMNA 2746/4885MAPK1 1463/4885 |
| US-20140206646-A1 | Heteroarylpiperidine and -piperazine derivatives as fungicides | CYP1A1, PRXL2A, CYP1A2 | L3MBTL1 1885/4885LMNA 2746/4885MAPK1 1463/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.