Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 4/20 | 0.52 |
| ▸ | BRD2 | P25440 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6971003 | 0.86 | BRD4 (0.45) | BRD4MAPTSMN1; SMN2LMNARAB9A | |
| SCHEMBL6971115 | 0.84 | BRD4 (0.45) | BRD4SMN1; SMN2LMNAALDH1A1KDM4E | |
| SCHEMBL6971266 | 0.83 | L3MBTL1 (0.44) | BRD4MAPTSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL6964190 | 0.82 | BRD4 (0.60) | BRD4SMN1; SMN2LMNARAB9AALDH1A1 | |
| SCHEMBL6971185 | 0.80 | L3MBTL1 (0.46) | BRD4MAPTSMN1; SMN2LMNARAB9A | |
| SCHEMBL7344427 | 0.79 | CA1 (0.54) | MAPTSMN1; SMN2LMNACA1CA2 | |
| SCHEMBL7344362 | 0.79 | CA1 (0.71) | MAPTSMN1; SMN2LMNACA1CA2 | |
| SCHEMBL7353072 | 0.77 | TSHR (0.61) | MAPTSMN1; SMN2LMNACA1CA2 | |
| SCHEMBL6966939 | 0.77 | TUBB4A (0.46) | BRD4MAPTLMNAALDH1A1MAPK1 | |
| SCHEMBL6955057 | 0.74 | BRD4 (0.57) | BRD4MAPTLMNAALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0620216-B1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO (JP) | 2003-01-08 | — | — | EP | disclosed |
| US-5521170-A | VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-28 | — | — | US | disclosed |
| EP-0620216-A1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-19 | — | — | EP | disclosed |