Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | BRD4 | O60885 | 2/20 | 0.45 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6971003 | 0.91 | BRD4 (0.45) | L3MBTL1BRD4CRBNMAPTALDH1A1 | |
| SCHEMBL6971266 | 0.88 | L3MBTL1 (0.44) | L3MBTL1BRD4CRBNMAPTALDH1A1 | |
| SCHEMBL6964190 | 0.84 | BRD4 (0.60) | L3MBTL1BRD4CRBNALDH1A1SMN1; SMN2 | |
| SCHEMBL6971115 | 0.80 | BRD4 (0.45) | L3MBTL1BRD4CRBNALDH1A1SMN1; SMN2 | |
| SCHEMBL6970387 | 0.80 | BRD4 (0.52) | BRD4MAPTALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL6970424 | 0.78 | ALDH1A1 (0.48) | L3MBTL1BRD4CRBNMAPTALDH1A1 | |
| SCHEMBL7346895 | 0.76 | ALDH1A1 (0.49) | L3MBTL1MAPTALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL7345342 | 0.75 | ALDH1A1 (0.67) | L3MBTL1MAPTALDH1A1LMNATDP1 | |
| SCHEMBL6966939 | 0.75 | TUBB4A (0.46) | BRD4CRBNMAPTALDH1A1LMNA | |
| SCHEMBL6970210 | 0.74 | BRD4 (0.59) | L3MBTL1BRD4CRBNMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0620216-B1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO (JP) | 2003-01-08 | — | — | EP | disclosed |
| US-5521170-A | VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-28 | — | — | US | disclosed |
| EP-0620216-A1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-19 | — | — | EP | disclosed |