Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 4/20 | 0.64 |
| ▸ | MAOB | P27338 | 4/20 | 0.62 |
| ▸ | KDM1A | O60341 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6964152 | 1.00 | HTR1A (0.64) | HTR1AMAOBKDM1A | |
| SCHEMBL829254 | 0.97 | HTR1A (0.64) | HTR1AMAOB | |
| Hydrochloric Acid SCHEMBL2558698 | 0.95 | HTR1A (0.62) | HTR1AMAOB | |
| Hydrochloric Acid SCHEMBL829918 | 0.95 | HTR1A (0.62) | HTR1AMAOB | |
| SCHEMBL7083797 | 0.95 | HTR1A (0.65) | HTR1AMAOB | |
| Hydrochloric Acid SCHEMBL2557258 | 0.94 | HTR1A (0.63) | HTR1AMAOB | |
| SCHEMBL29564155 | 0.90 | HTR1A (0.55) | HTR1AMAOBKDM1A | |
| SCHEMBL20404 | 0.90 | HTR1A (0.55) | HTR1AMAOBKDM1A | |
| SCHEMBL13469510 | 0.88 | HTR1A (0.79) | HTR1AMAOB | |
| SCHEMBL26634553 | 0.88 | HTR1A (0.62) | HTR1AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0620216-B1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO (JP) | 2003-01-08 | — | — | EP | disclosed |
| WO-1996033723-A2 | USE OF BENZAMIDE DERIVATIVES FOR TREATING AND/OR PREVENTING MENIERE'S SYNDROME AND MOTION SICKNESS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-10-31 | — | — | WO | disclosed |
| US-5521170-A | VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-28 | — | — | US | disclosed |
| EP-0620216-A1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-19 | — | — | EP | disclosed |