SCHEMBL7083797

SCHEMBL7083797

O=C1c2ccccc2C(=O)N1CCCCCN1CCNCC1

nearest known ligand 0.65

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HTR1A P08908 3/20 0.65
MAOB P27338 3/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL2557258 0.98 HTR1A (0.63) HTR1AMAOB
SCHEMBL829254 0.98 HTR1A (0.64) HTR1AMAOB
Hydrochloric Acid SCHEMBL2558698 0.97 HTR1A (0.62) HTR1AMAOB
Hydrochloric Acid SCHEMBL829918 0.97 HTR1A (0.62) HTR1AMAOB
SCHEMBL6970401 0.95 HTR1A (0.64) HTR1AMAOB
SCHEMBL6964152 0.95 HTR1A (0.64) HTR1AMAOB
SCHEMBL20404 0.89 HTR1A (0.55) HTR1AMAOB
SCHEMBL29564155 0.89 HTR1A (0.55) HTR1AMAOB
SCHEMBL14028451 0.87 HTR1A (0.79) HTR1AMAOB
SCHEMBL8557005 0.85 HTR1A (0.70) HTR1AMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015189650-A1 CLOPIDOGREL FOR USE IN THE TREATMENT OF BENIGN PROSTATIC HYPERPLASIA SKILLPHARM KFT. (HU) 2015-12-17 WO disclosed
EP-1346983-A3 Phthalimido arylpiperazines as alpha 1A receptor antagonists useful in the treatment of benign prostatic hyperplasia Ortho-Mcneil Pharmaceutical, Inc. (US) 2003-12-03 EP disclosed
EP-1346983-A2 Phthalimido arylpiperazines as alpha 1A receptor antagonists useful in the treatment of benign prostatic hyperplasia Ortho-Mcneil Pharmaceutical, Inc. (US) 2003-09-24 EP disclosed