SCHEMBL29564155

SCHEMBL29564155

O=C1c2ccccc2C(=O)N1CCN1CCNCC1

nearest known ligand 0.62

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
HTR1A P08908 6/20 0.55
KDM1A O60341 1/20 0.54
MAOB P27338 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20404 1.00 HTR1A (0.55) HTR1AKDM1AMAOB
SCHEMBL26634553 0.91 HTR1A (0.62) HTR1AMAOB
SCHEMBL6970401 0.90 HTR1A (0.64) HTR1AKDM1AMAOB
SCHEMBL829254 0.90 HTR1A (0.64) HTR1AMAOB
SCHEMBL6964152 0.90 HTR1A (0.64) HTR1AKDM1AMAOB
SCHEMBL7083797 0.89 HTR1A (0.65) HTR1AMAOB
Hydrochloric Acid SCHEMBL829918 0.89 HTR1A (0.62) HTR1AMAOB
Hydrochloric Acid SCHEMBL2558698 0.89 HTR1A (0.62) HTR1AMAOB
Hydrochloric Acid SCHEMBL2557258 0.87 HTR1A (0.63) HTR1AMAOB
SCHEMBL23164620 0.87 HTR1A (0.67) HTR1AMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12539650-B2 Method for making embedded hydrogel contact lenses ALCON INC. (CH) 2026-02-03 US claimed
EP-4514595-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES Alcon Inc. (CH) 2025-03-05 EP claimed
EP-4240578-B1 METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES ALCON INC (CH) 2024-12-18 EP claimed
US-11886045-B2 Method for making photochromic contact lenses ALCON INC. (CH) 2024-01-30 US claimed
WO-2023209570-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES ALCON INC. (CH) 2023-11-02 WO claimed
US-20230339149-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES ALCON INC. (CH) 2023-10-26 US claimed
EP-4240578-A1 METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES Alcon Inc. (CH) 2023-09-13 EP claimed
WO-2022097048-A1 METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES ALCON INC. (CH) 2022-05-12 WO claimed
US-20220137433-A1 METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES ALCON INC. (CH) 2022-05-05 US claimed
US-20260131506-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES ALCON INC (CH) 2026-05-14 US disclosed
US-12539650-B2 Method for making embedded hydrogel contact lenses ALCON INC. (CH) 2026-02-03 US disclosed
EP-4514595-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES Alcon Inc. (CH) 2025-03-05 EP disclosed
EP-4240578-B1 METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES ALCON INC (CH) 2024-12-18 EP disclosed
US-11886045-B2 Method for making photochromic contact lenses ALCON INC. (CH) 2024-01-30 US disclosed
WO-2023209570-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES ALCON INC. (CH) 2023-11-02 WO disclosed
US-20230339149-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES ALCON INC. (CH) 2023-10-26 US disclosed
EP-4240578-A1 METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES Alcon Inc. (CH) 2023-09-13 EP disclosed
CN-114524781-A Lipid composition 阿布特斯生物制药公司 2022-05-24 CN disclosed
WO-2022097048-A1 METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES ALCON INC. (CH) 2022-05-12 WO disclosed
US-20220137433-A1 METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES ALCON INC. (CH) 2022-05-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12539650-B2 Method for making embedded hydrogel contact lenses INF2, CRYZ, CRYAA HTR1A 4807/4885KDM1A 1815/4885MAOB 4396/4885
US-20260131506-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES CRYZ, CRYAB, CRYAA HTR1A 4758/4885KDM1A 3012/4885MAOB 4726/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.