Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | GABRP | O00591 | 3/20 | 0.47 |
| ▸ | GABRD | O14764 | 3/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.47 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.47 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.47 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.47 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.47 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.47 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6970766 | 0.81 | ALDH1A1 (0.49) | PKMMEN1KMT2AL3MBTL1CYP1A2 | |
| SCHEMBL18780239 | 0.78 | PKM (0.56) | PKMMEN1KMT2AL3MBTL1CYP1A2 | |
| SCHEMBL7676239 | 0.78 | NPSR1 (0.56) | PKMMEN1KMT2AL3MBTL1CYP1A2 | |
| SCHEMBL7821180 | 0.78 | PKM (0.54) | PKMMEN1KMT2AL3MBTL1CYP1A2 | |
| SCHEMBL16592104 | 0.77 | NPSR1 (0.55) | PKMMEN1KMT2AL3MBTL1CYP1A2 | |
| SCHEMBL22809569 | 0.76 | PKM (0.52) | PKMMEN1KMT2AL3MBTL1CYP1A2 | |
| SCHEMBL9768245 | 0.76 | POLB (0.46) | MEN1KMT2AL3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL29953834 | 0.75 | AGBL2 (0.37) | PKMMEN1KMT2AL3MBTL1CYP1A2 | |
| SCHEMBL7691905 | 0.75 | ALDH1A1 (0.46) | PKMMEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL7671680 | 0.75 | KMT2A (0.51) | MEN1KMT2AL3MBTL1CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |