Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6970770 | 0.78 | PKM (0.50) | PKMKMT2AMEN1L3MBTL1CYP1A2 | |
| SCHEMBL7821174 | 0.76 | PKM (0.65) | PKMKMT2AMEN1L3MBTL1ALDH1A1 | |
| SCHEMBL707320 | 0.76 | ALDH1A1 (0.63) | KMT2AMEN1CYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL18780239 | 0.75 | PKM (0.56) | PKMKMT2AMEN1L3MBTL1CYP1A2 | |
| SCHEMBL6970766 | 0.75 | ALDH1A1 (0.49) | PKMKMT2AMEN1L3MBTL1CYP1A2 | |
| SCHEMBL14234225 | 0.74 | PKM (0.53) | PKMKMT2AMEN1L3MBTL1CYP1A2 | |
| Acetic Acid SCHEMBL28420283 | 0.73 | ALDH1A1 (0.52) | KMT2AMEN1L3MBTL1CYP1A2CYP2C19 | |
| SCHEMBL28110473 | 0.72 | ALDH1A1 (0.74) | KMT2AMEN1L3MBTL1ALDH1A1GAA | |
| SCHEMBL14920934 | 0.72 | CYP1A2 (0.58) | KMT2AMEN1L3MBTL1CYP1A2CYP2C19 | |
| SCHEMBL7676239 | 0.72 | NPSR1 (0.56) | PKMKMT2AMEN1L3MBTL1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |