Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 17/20 | 0.59 |
| ▸ | DRD4 | P21917 | 17/20 | 0.59 |
| ▸ | DRD3 | P35462 | 17/20 | 0.59 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.52 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.52 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.51 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.51 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.51 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.51 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.51 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.51 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6972143 | 0.99 | DRD2 (0.58) | DRD2DRD4DRD3GRIN1GRIN2B | |
| SCHEMBL6971825 | 0.92 | DRD2 (0.51) | DRD2DRD4DRD3GRIN1GRIN2B | |
| SCHEMBL6955492 | 0.92 | DRD2 (0.54) | DRD2DRD4DRD3GRIN1GRIN2B | |
| SCHEMBL6964674 | 0.85 | DRD2 (0.48) | DRD2DRD4DRD3CHRM1 | |
| SCHEMBL6965133 | 0.85 | DRD2 (0.62) | DRD2DRD4DRD3GRIN1GRIN2B | |
| Hydrochloric Acid SCHEMBL6959218 | 0.84 | DRD2 (0.61) | DRD2DRD4DRD3GRIN1GRIN2B | |
| SCHEMBL5498800 | 0.82 | DRD2 (0.59) | DRD2DRD4DRD3GRIN1GRIN2B | |
| Hydrochloric Acid SCHEMBL7168274 | 0.82 | DRD2 (0.58) | DRD2DRD4DRD3GRIN1GRIN2B | |
| SCHEMBL7087330 | 0.81 | DRD2 (0.56) | DRD2DRD4DRD3GRIN1GRIN2B | |
| SCHEMBL6971120 | 0.79 | DRD2 (0.42) | DRD2DRD4DRD3ADRA1DADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934312-B1 | 1,4-DISUBSTITUTED PIPERAZINES | NOVO NORDISK AS (DK) | 2003-03-19 | — | — | EP | claimed |