Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3871114 | 0.81 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2GAAKDM4EMAPT | |
| SCHEMBL20522286 | 0.80 | QPCT (0.50) | ALDH1A1SMN1; SMN2GAAKDM4EMAPT | |
| SCHEMBL9779941 | 0.80 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2RAB9AGAAKDM4E | |
| SCHEMBL9756822 | 0.80 | LMNA (0.60) | ALDH1A1SMN1; SMN2KDM4EMAPTLMNA | |
| SCHEMBL6977216 | 0.79 | SIRT2 (0.53) | ALDH1A1SMN1; SMN2RAB9AGAAKDM4E | |
| Hydrochloric Acid SCHEMBL8170951 | 0.79 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2RAB9AGAAKDM4E | |
| SCHEMBL9829793 | 0.77 | TOP2A (0.53) | ALDH1A1SMN1; SMN2RAB9AMAPTLMNA | |
| SCHEMBL13737098 | 0.77 | HDAC3 (0.48) | ALDH1A1SMN1; SMN2GAAKDM4EMAPT | |
| SCHEMBL28325177 | 0.77 | SMN1; SMN2 (0.48) | ALDH1A1SMN1; SMN2RAB9AGAAMAPT | |
| SCHEMBL9201178 | 0.76 | PDK1 (0.42) | ALDH1A1SMN1; SMN2RAB9AGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1021411-B1 | BENZAMIDE DERIVATIVES AS THROMBIN INHIBITORS | GLAXO GROUP LTD (GB) | 2003-03-05 | — | — | EP | disclosed |
| US-6326386-B1 | ANTICOAGULANT | GLAXO GROUP LIMITED (GB) | 2001-12-04 | — | — | US | disclosed |
| EP-1021411-A1 | BENZAMIDE DERIVATIVES AS THROMBIN INHIBITORS | GLAXO GROUP LIMITED (GB) | 2000-07-26 | — | — | EP | disclosed |
| WO-1997022589-A1 | BENZAMIDE DERIVATIVES AS THROMBIN INHIBITORS | GLAXO GROUP LIMITED (GB) | 1997-06-26 | — | — | WO | disclosed |