Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | UBE2M | P61081 | 1/20 | 0.39 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.39 |
| ▸ | KLK6 | Q92876 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6964956 | 0.90 | L3MBTL1 (0.47) | ALDH1A1LMNANPC1RAB9ANPSR1 | |
| SCHEMBL6970818 | 0.83 | MEN1 (0.39) | ALDH1A1LMNANPC1RAB9ATSHR | |
| SCHEMBL6966662 | 0.81 | NPSR1 (0.44) | ALDH1A1LMNANPC1RAB9ANPSR1 | |
| SCHEMBL6970481 | 0.74 | MEN1 (0.39) | ALDH1A1LMNANPC1RAB9ANPSR1 | |
| SCHEMBL26452772 | 0.69 | KMT2A (0.66) | ALDH1A1SLC7A5NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL25765391 | 0.69 | MEN1 (0.53) | ALDH1A1LMNAHTTSMN1; SMN2POLB | |
| SCHEMBL6175213 | 0.67 | SLC7A5 (0.56) | SLC7A5 | |
| SCHEMBL30240826 | 0.64 | SLC7A5 (0.59) | SLC7A5 | |
| SCHEMBL14541727 | 0.64 | SLC7A5 (0.59) | SLC7A5 | |
| SCHEMBL19951196 | 0.64 | LMNA (0.59) | ALDH1A1LMNASLC7A5NPC1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |