Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 5/20 | 0.40 |
| ▸ | MMP2 | P08253 | 4/20 | 0.40 |
| ▸ | MMP8 | P22894 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MMP3 | P08254 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | RYR2 | Q92736 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6977761 | 0.90 | HRH3 (0.39) | ALDH1A1PPARDMMP3 | |
| SCHEMBL6735054 | 0.85 | MMP13 (0.52) | MMP13MMP2MMP8ALDH1A1MMP9 | |
| SCHEMBL6972751 | 0.84 | CYP4F2 (0.37) | KMT2A | |
| SCHEMBL6732559 | 0.78 | MMP13 (0.53) | MMP13MMP2MMP8ALDH1A1HTT | |
| SCHEMBL6727303 | 0.76 | MMP13 (0.62) | MMP13MMP2MMP8ALDH1A1MMP9 | |
| SCHEMBL6735645 | 0.74 | MMP1 (0.47) | MMP13MMP2MMP8KMT2AMEN1 | |
| SCHEMBL6727259 | 0.73 | MMP1 (0.43) | MMP13MMP2MMP8ALDH1A1HTT | |
| SCHEMBL6969747 | 0.72 | MMP13 (0.50) | MMP13MMP2MMP8ALDH1A1MMP9 | |
| SCHEMBL6827826 | 0.72 | CYP4F2 (0.43) | MMP13MMP2MMP8ALDH1A1MMP9 | |
| SCHEMBL6730211 | 0.70 | HDAC3 (0.46) | MMP13MMP2MMP8ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1053233-B1 | HYDROXAMIC AND CARBOXYLIC ACID DERIVATIVES | DARWIN DISCOVERY LTD (GB) | 2003-08-20 | — | — | EP | claimed |