Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 2/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | PTAFR | P25105 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6968315 | 0.85 | CYP4F2 (0.45) | CYP4F2CYP4A11CHRNB2CHRNA4KMT2A | |
| SCHEMBL6977761 | 0.84 | HRH3 (0.39) | FFAR1 | |
| SCHEMBL6735747 | 0.79 | CHRNB2 (0.42) | CYP4F2CYP4A11CHRNB2CHRNA4KMT2A | |
| SCHEMBL6976704 | 0.74 | MMP1 (0.40) | CYP4F2CYP4A11CHRNB2CHRNA4KMT2A | |
| SCHEMBL6827826 | 0.73 | CYP4F2 (0.43) | CYP4F2CYP4A11 | |
| SCHEMBL6727249 | 0.69 | MMP13 (0.41) | KMT2AEPHX2DRD2DRD3 | |
| SCHEMBL6735054 | 0.69 | MMP13 (0.52) | CYP4F2CYP4A11 | |
| SCHEMBL6727259 | 0.68 | MMP1 (0.43) | CYP4F2CYP4A11 | |
| SCHEMBL6829624 | 0.67 | CHRNB2 (0.41) | CHRNB2CHRNA4EPHX2 | |
| SCHEMBL6735645 | 0.66 | MMP1 (0.47) | CYP4F2CYP4A11KMT2AEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1053233-B1 | HYDROXAMIC AND CARBOXYLIC ACID DERIVATIVES | DARWIN DISCOVERY LTD (GB) | 2003-08-20 | — | — | EP | claimed |