Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 5/20 | 0.50 |
| ▸ | MMP2 | P08253 | 4/20 | 0.50 |
| ▸ | MMP8 | P22894 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 3/20 | 0.43 |
| ▸ | MMP3 | P08254 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 2/20 | 0.42 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | AOC2 | O75106 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | DHFR | P00374 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6976767 | 0.89 | USP2 (0.45) | MMP13MMP2MMP8LMNAMMP9 | |
| SCHEMBL6735054 | 0.84 | MMP13 (0.52) | MMP13MMP2MMP8ALDH1A1LMNA | |
| SCHEMBL6976704 | 0.81 | MMP1 (0.40) | MMP13GAAMMP1 | |
| SCHEMBL6732559 | 0.81 | MMP13 (0.53) | MMP13MMP2MMP8ALDH1A1LMNA | |
| SCHEMBL6727303 | 0.79 | MMP13 (0.62) | MMP13MMP2MMP8ALDH1A1LMNA | |
| SCHEMBL6976225 | 0.78 | MMP13 (0.45) | MMP13MMP2MMP8ALDH1A1LMNA | |
| SCHEMBL6730211 | 0.73 | HDAC3 (0.46) | MMP13MMP2MMP8ALDH1A1LMNA | |
| SCHEMBL6735645 | 0.73 | MMP1 (0.47) | MMP13MMP2MMP8MMP9MMP3 | |
| SCHEMBL6971676 | 0.72 | MMP13 (0.40) | MMP13MMP2MMP8ALDH1A1LMNA | |
| SCHEMBL6953375 | 0.72 | SMN1; SMN2 (0.46) | MMP13MMP2MMP8LMNAMMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1053233-B1 | HYDROXAMIC AND CARBOXYLIC ACID DERIVATIVES | DARWIN DISCOVERY LTD (GB) | 2003-08-20 | — | — | EP | claimed |