Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6967633 | 0.79 | POLB (0.42) | GAANPSR1TDP1ALDH1A1HPGD | |
| SCHEMBL6971199 | 0.79 | NPSR1 (0.34) | GAANPSR1TDP1ALDH1A1HPGD | |
| SCHEMBL161002 | 0.76 | HDAC8 (0.48) | GAAHPGD | |
| SCHEMBL6971685 | 0.74 | GAA (0.39) | GAANPC1HPGDRAB9A | |
| SCHEMBL1379363 | 0.73 | NPC1 (0.52) | GAANPSR1TDP1GLACACNA1B | |
| SCHEMBL6971606 | 0.72 | — | — | |
| SCHEMBL8994450 | 0.71 | ALDH1A1 (0.35) | GAATDP1ALDH1A1HPGD | |
| SCHEMBL9629049 | 0.70 | GAA (0.46) | GAAALDH1A1NPC1HPGDRAB9A | |
| SCHEMBL6960682 | 0.69 | MAPT (0.53) | GAAALDH1A1NPC1HPGDRAB9A | |
| SCHEMBL10644432 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1205181-C | Matrix metalloproteinase inhibitors | LEO PHARMACEUTICAL PRODUOTS LT (DK) | 2005-06-08 | — | — | CN | disclosed |
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |