Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6971704 | 0.79 | GAA (0.35) | NPSR1TDP1ALDH1A1GAAHPGD | |
| SCHEMBL160225 | 0.79 | NPSR1 (0.47) | NPSR1ALDH1A1LMNACYP1A2CYP3A4 | |
| SCHEMBL6967633 | 0.75 | POLB (0.42) | NPSR1TDP1ALDH1A1ALOX12LMNA | |
| SCHEMBL23198162 | 0.69 | FAAH (0.49) | ALDH1A1CYP1A2 | |
| SCHEMBL3316333 | 0.69 | SLC1A2 (0.39) | NPSR1ALDH1A1LMNAGAACYP1A2 | |
| SCHEMBL6971606 | 0.69 | — | — | |
| SCHEMBL689066 | 0.68 | GAA (0.41) | NPSR1TDP1ALDH1A1LMNAGAA | |
| SCHEMBL7648459 | 0.68 | LMNA (0.33) | NPSR1LMNA | |
| SCHEMBL3087004 | 0.68 | ALDH1A1 (0.37) | NPSR1ALDH1A1GAACYP1A2CYP3A4 | |
| SCHEMBL8994450 | 0.67 | ALDH1A1 (0.35) | TDP1ALDH1A1GAACYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |