Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | TAS2R38 | P59533 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6973539 | 0.81 | TAS2R38 (0.57) | MAPTSMN1; SMN2GAACYP1A2CYP2C19 | |
| SCHEMBL6965156 | 0.81 | MAPT (0.48) | MAPTSMN1; SMN2GAAALDH1A1KMT2A | |
| SCHEMBL746119 | 0.78 | ALDH1A1 (0.47) | MAPTSMN1; SMN2ALDH1A1HPGDRAB9A | |
| SCHEMBL7102655 | 0.76 | MAOB (0.53) | MAPTGAAALDH1A1KMT2AMEN1 | |
| SCHEMBL23812525 | 0.76 | GAA (0.84) | MAPTSMN1; SMN2GAACYP1A2CYP2C19 | |
| SCHEMBL1276402 | 0.76 | GAA (0.84) | MAPTSMN1; SMN2GAACYP1A2CYP2C19 | |
| SCHEMBL14360821 | 0.74 | ALDH1A1 (0.70) | MAPTSMN1; SMN2GAACYP1A2CYP2C19 | |
| SCHEMBL60383 | 0.73 | — | — | |
| SCHEMBL50031 | 0.73 | HSD17B10 (0.57) | MAPTSMN1; SMN2GAACYP1A2CYP2C19 | |
| SCHEMBL10658809 | 0.73 | EPHX1 (0.71) | SMN1; SMN2ALDH1A1HPGDRAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |