Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.51 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4901240 | 0.92 | HRH4 (0.44) | HRH3HRH4L3MBTL1TDP1ALDH1A1 | |
| SCHEMBL4903117 | 0.85 | TSHR (0.46) | HRH3HRH4ALDH1A1TSHRHTT | |
| SCHEMBL7664922 | 0.75 | TAAR1 (0.43) | HRH3TSHRKMT2A | |
| SCHEMBL6962088 | 0.74 | HRH4 (0.43) | HRH3HRH4L3MBTL1TDP1ALDH1A1 | |
| SCHEMBL4893200 | 0.71 | HRH4 (0.45) | HRH3HRH4L3MBTL1TDP1ALDH1A1 | |
| SCHEMBL6966941 | 0.70 | IDO1 (0.42) | L3MBTL1TDP1ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL4069939 | 0.69 | TDP1 (0.64) | HRH3HRH4L3MBTL1TDP1TSHR | |
| Proxyfan SCHEMBL15929504 | 0.68 | HRH3 (1.00) | HRH3HRH4 | |
| SCHEMBL7479206 | 0.68 | HRH3 (0.44) | HRH3HRH4L3MBTL1TDP1ALDH1A1 | |
| SCHEMBL7474823 | 0.68 | HRH4 (0.44) | HRH3HRH4L3MBTL1TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786455-B1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO (JP) | 2003-12-03 | — | — | EP | disclosed |
| US-6147097-A | METHOD FOR TREATING AIDS | SHIONOGI & CO., LTD. (JP) | 2000-11-14 | — | — | US | disclosed |
| US-5910506-A | IMIDAZOLE DERIVATIVES, E.G.5-(3,5-DICHLOROPHENYLTHIO)-1,2-DIMETHYL-4-ISOPROPYL-1H-IMIDAZOLE; VIRICIDES; AIDS; NONTOXIC | SHIONOGI & CO., LTD. (JP) | 1999-06-08 | — | — | US | disclosed |
| EP-0786455-A1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 1997-07-30 | — | — | EP | disclosed |