Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLRA3 | O75311 | 1/20 | 0.31 |
| ▸ | GLRB | P48167 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6964081 | 0.78 | NPC1 (0.39) | NPC1 | |
| SCHEMBL6969830 | 0.78 | GLRA3 (0.34) | GLRA3GLRBMEN1NPC1KMT2A | |
| SCHEMBL9223224 | 0.67 | ALDH1A1 (0.44) | NPC1KMT2A | |
| SCHEMBL6965564 | 0.64 | — | — | |
| SCHEMBL14284014 | 0.64 | ALDH1A1 (0.32) | — | |
| SCHEMBL8304086 | 0.62 | NOTUM (0.33) | GLRA3GLRBNPC1 | |
| SCHEMBL10846303 | 0.61 | ALDH1A1 (0.48) | MEN1NPC1KMT2A | |
| SCHEMBL7321755 | 0.59 | RAB9A (0.41) | MEN1NPC1KMT2A | |
| SCHEMBL2809402 | 0.59 | CYP3A4 (0.38) | MEN1KMT2A | |
| SCHEMBL403704 | 0.59 | CA12 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | claimed |
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |