Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLRA3 | O75311 | 1/20 | 0.34 |
| ▸ | GLRB | P48167 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | TYR | P14679 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6966557 | 0.74 | RAB9A (0.42) | ALDH1A1POLBSMN1; SMN2MEN1NPC1 | |
| SCHEMBL14284014 | 0.69 | ALDH1A1 (0.32) | ALDH1A1CA2POLBTYRSMN1; SMN2 | |
| SCHEMBL8304086 | 0.67 | NOTUM (0.33) | GLRA3GLRBSMN1; SMN2NPC1 | |
| SCHEMBL6965564 | 0.65 | — | — | |
| SCHEMBL11696604 | 0.63 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2NPC1KMT2AKDM4E | |
| SCHEMBL183194 | 0.61 | RAB9A (0.42) | ALDH1A1MEN1NPC1KMT2AKDM4E | |
| SCHEMBL501929 | 0.61 | POLB (0.44) | GLRA3GLRBALDH1A1POLBMEN1 | |
| SCHEMBL1800550 | 0.61 | NPC1 (0.42) | ALDH1A1SMN1; SMN2NPC1KDM4E | |
| SCHEMBL9223224 | 0.61 | ALDH1A1 (0.44) | L3MBTL1ALDH1A1CA2POLBSMN1; SMN2 | |
| SCHEMBL1005715 | 0.60 | CA2 (0.45) | GLRA3GLRBALDH1A1CA2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |