Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 2/20 | 0.39 |
| ▸ | CES1 | P23141 | 2/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.39 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1672797 | 0.80 | FFAR1 (0.48) | FFAR1HPGDMAPTHSD17B10SMN1; SMN2 | |
| SCHEMBL2509039 | 0.80 | FFAR1 (0.48) | FFAR1HPGDMAPTHSD17B10SMN1; SMN2 | |
| SCHEMBL3087191 | 0.80 | FFAR1 (0.48) | FFAR1HPGDMAPTHSD17B10SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11847778 | 0.78 | FFAR1 (0.46) | FFAR1HPGDMAPTHSD17B10SMN1; SMN2 | |
| Diphenylsulfane SCHEMBL6843735 | 0.77 | HPGD (0.62) | FFAR1HPGDMAPTHSD17B10SMN1; SMN2 | |
| Diphenylsulfane SCHEMBL7024955 | 0.77 | HPGD (0.62) | FFAR1HPGDMAPTHSD17B10SMN1; SMN2 | |
| Diphenylsulfane SCHEMBL19056221 | 0.77 | HPGD (0.62) | FFAR1HPGDMAPTHSD17B10SMN1; SMN2 | |
| SCHEMBL11205280 | 0.76 | CA12 (0.46) | FFAR1HPGDMAPTHSD17B10SMN1; SMN2 | |
| SCHEMBL17322710 | 0.76 | FFAR1 (0.44) | FFAR1HPGDMAPTHSD17B10SMN1; SMN2 | |
| SCHEMBL3038672 | 0.76 | SIRT1 (0.47) | FFAR1HPGDMAPTHSD17B10SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | claimed |
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |