Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.34 |
| ▸ | KDR | P35968 | 2/20 | 0.34 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.34 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.34 |
| ▸ | TDP2 | O95551 | 1/20 | 0.34 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.34 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.33 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.33 |
| ▸ | CLK2 | P49760 | 1/20 | 0.33 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13184233 | 0.74 | DYRK1A (0.41) | HSP90AA1NPC1GAAMAPTCYP3A4 | |
| SCHEMBL3229317 | 0.71 | HCAR2 (0.37) | CYP3A4MAPK1P2RX7KMT2A | |
| SCHEMBL1640767 | 0.69 | PDE4D (0.59) | HSP90AA1HSP90AB1PDE4DCSNK2A2KDR | |
| SCHEMBL10919855 | 0.68 | PDE4D (0.45) | ALDH1A1PDE4DTDP2SMN1; SMN2MAPT | |
| SCHEMBL10923051 | 0.68 | HSP90AA1 (0.41) | HSP90AA1HSP90AB1ALDH1A1GAAMAPT | |
| SCHEMBL29656885 | 0.64 | ALDH1A1 (0.41) | NPC1RAB9AALDH1A1TDP2SMN1; SMN2 | |
| SCHEMBL22498528 | 0.64 | ALDH1A1 (0.41) | NPC1RAB9AALDH1A1TDP2SMN1; SMN2 | |
| SCHEMBL4382163 | 0.63 | RAB9A (0.49) | HSP90AA1HSP90AB1RAB9AALDH1A1GAA | |
| SCHEMBL12106580 | 0.63 | CYP1A2 (0.39) | ALDH1A1PDE4DCSNK2A2KDRCSNK2B | |
| SCHEMBL12106575 | 0.63 | PDE4D (0.43) | HSP90AA1HSP90AB1ALDH1A1PDE4DCSNK2A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0784055-B1 | PYRIMIDINYLPYRAZOLE DERIVATIVE | DAIICHI SEIYAKU CO (JP) | 2003-02-12 | — | — | EP | disclosed |